Microb-AI-ome Vision

Federated artificial intelligence for privacy-preserving colorectal cancer research

Microb-AI-ome explores how artificial intelligence and microbiome science can support smarter, more precise, and privacy-preserving colorectal cancer screening.

Why does this matter?

340,000+

colorectal cancer cases in Europe every year

156,000

deaths linked to colorectal cancer in Europe

€20 billion

estimated annual economic burden

37.4%

unnecessary colonoscopies after positive FIT tests

The challenge

Important microbiome data exists, but it remains fragmented

Colorectal cancer screening often relies on FIT testing to predict whether a colonoscopy is needed. However, many patients still undergo invasive procedures that ultimately do not detect cancer.

At the same time, valuable microbiome datasets remain distributed across institutions and countries, making integration difficult under strict privacy regulations.

Current barriers

  • Isolated national datasets
  • Strict privacy requirements
  • Limited large-scale AI training
  • Need for more precise screening tools
How it works

Federated AI: the model travels, the data stays protected

1

Local databases

Clinical and microbiome data remain securely stored at local institutions.

2

Federated learning

AI models learn across distributed datasets without centralising sensitive data.

3

Smarter screening

The resulting tools aim to improve colorectal cancer stratification and screening.

A future where colorectal cancer screening becomes smarter

Microb-AI-ome combines microbiome science, artificial intelligence, and European collaboration to support more precise, privacy-aware, and patient-centred colorectal cancer screening.

Meet the consortium